DNA Banking in Epidemiologic Studies

Sample size estimation in epidemiologic studies

This review basically provided a conceptual framework for sample size calculation in epidemiologic studies with various designs and outcomes. The formula requirement of sample size was drawn based on statistical principles for both descriptive and comparative studies. The required sample size was estimated and presented graphically with different effect sizes and power of statistical test at 95...

Methodological issues of confounding in analytical epidemiologic studies

Background: Confounding can be thought of as mixing the effect of exposure on the risk of disease with a third factor which distorts the measure of association such as risk ratio or odds ratio. This bias arises because of complex functional relationship of confounder with both exposure and disease (outcome). In this article, we provided a conceptual framework review of confounding issues in epi...

Epidemiologic Studies in Whooping Cough *

The following procedures were employed in the three studies: (I ) Cases of diagnosed or suspected whooping cough reported by the New Haven Hospital Dispensary or, occasionally, by the local health department or by practitioners were investigated. (2) The families of the diagnosed cases were seen and cough-plates were made from each member of the family. (3) Answers to specific questions pertain...

Participation rates in epidemiologic studies.

Participation rates for epidemiologic studies have been declining during the past 30 years with even steeper declines in recent years. This wholesale decrease in participation rate, or at the very least the increase in refusal, has, quite understandably, occasioned some concern among epidemiologists who have long considered a high study participation rate as one of the hallmarks of a "good" epi...

Measurement Error in Epidemiologic Studies